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Correlation of PM2.5 pollution and daily mortality rate of cardiovascular and cerebrovascular diseases in Northeast China through PM2.5 sources analysis
Qianqi Hong, Yang Zhao, Jing Wang, Hongyan Sun, Lanxin Deng, Jingjing Cao, Cheng Wang
2024, 4(4): 193-201. doi: 10.1515/fzm-2024-0019
Keywords: PM2.5, cardio-cerebrovascular diseases, daily mortality, time series, PMF
  Objective   This study aims to evaluate the relationship between PM2.5 concentration and daily mortality rate from cardiovascular and cerebrovascular diseases (CCVD) in cold regions of northern China, as well as to identify the primary sources of PM2.5.   Methods   A time series analysis model was used to calculate the exposure-response relationship between PM2.5 and CCVD mortality in Harbin. Positive matrix factorization (PMF) was employed to analyze the sources of PM2.5.   Results   After adjusting for multiple pollutant combinations, the maximum excess risk of cardio-cerebrovascular death on the day of PM2.5 exposure was 0.42% (95% CI: 0.15%-0.70%). Stratification by gender and age revealed that the elderly individuals and men were particularly susceptible to PM2.5 exposure. The source analysis identified seven major pollution sources contributing to PM2.5 in Harbin.   Conclusion   Our findings strengthen the evidence that PM2.5 is an independent risk factor for daily CCVD mortality, identify vulnerable populations that require special attention, and pinpoint the primary sources of PM2.5 in Harbin. These findings provide reference points for effectively reducing the health risks associated with PM2.5 exposure.
The associations between dietary minerals, obesity and hypertension in cold region
Weiqi Wang, Hongyan Sun, Rui Zhou, Ling Li, Cheng Wang
2026, 6(1): 15-24. doi: 10.1515/fzm-2026-0002
Keywords: mineral, obesity, abdominal obesity, hypertension
  Objective  This study aimed to compare dietary patterns and nutrient intakes between cold and non-cold regions of China, and to assess the associations between dietary mineral intake and the risks of overweight, obesity, abdominal obesity and hypertension in residents of cold region.  Methods  A total of 12, 190 participants from the China Health and Nutrition Survey were included, of whom 1261 were residents of Heilongjiang province. Dietary intake was assessed using three consecutive 24 h individual dietary recalls. General linear models were applied to compare dietary differences between Heilongjiang and other provinces, and Cox proportional hazard models were used to evaluate the associations between mineral intake and the aforementioned health outcomes among Heilongjiang residents.  Results  Significant differences were observed in the intake of fruits, vegetables, nuts, whole grains, processed meats, vitamin C, calcium, phosphorus, and magnesium between Heilongjiang and other provinces (all P < 0.05). In Heilongjiang residents, higher intakes of phosphorus, iron, and calcium were more strongly associated with lower risks of overweight, obesity, abdominal obesity, and hypertension than potassium or magnesium. The hazard ratios (HRs) and 95% confidence intervals (CIs) across tertiles of calcium, phosphorus and iron intake were as follows: 0.37 (0.28-0.50), 0.37 (0.28-0.49), 0.48 (0.36-0.64) for overweight; 0.53 (0.35-0.79), 0.50 (0.34-0.75), 0.45 (0.30-0.69) for obesity; 0.49 (0.38-0.64), 0.52 (0.40-0.66), 0.59 (0.46-0.77) for abdominal obesity; and 0.42 (0.32-0.54), 0.42 (0.33-0.53), 0.49 (0.38-0.63) for hypertension.  Conclusion  Distinct dietary patterns exist between cold and other region of China. Adequate intake of phosphorus, iron, calcium, potassium and magnesium consumption may help protect against obesity and hypertension in populations living in cold environments.